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Updated: Aug 19, 2026

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Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Polymerase chain reaction amplification as a diagnostic tool in culture-negative multiple-valve endocarditis
Navid Madershahian1, Justus T Strauch, Martin Breuer
1Department of Cardiothoracic and Vascular Surgery, Friedrich-Schiller University Jena, Jena, Germany.
The Annals of Thoracic Surgery
|March 1, 2005
Abstract:
We report a case of culture-negative infectious endocarditis in a 17-year-old boy in which the etiologic diagnosis could only be provided by polymerase chain reaction amplification and sequencing of the bacterial 16S rRNA gene from valve tissue.
