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Updated: Aug 19, 2026
Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
Published on: August 4, 2018
PlasmaKinetic bipolar vessel sealing: burst pressures and thermal spread in an animal model
Paul K Pietrow1, Alon Z Weizer, James O L'Esperance
1Department of Urology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Background And Purpose:
Laparoscopic bipolar instruments are commonly employed to cauterize and divide tissue. A next-generation bipolar device has been developed that employs vapor pulse coagulation energy. We assessed the vessel-sealing capability of this device and quantified thermal spread during application.
Materials And Methods:
Bilateral laparoscopic nephrectomy was performed on six common swine >25 kg. Five-millimeter clips and surgical staplers (US Surgical, Norwalk, CT) were utilized to perform nephrectomy on one side, while the Gyrus PlasmaKinetic bipolar device (Minneapolis, MN) was employed for the contralateral nephrectomy. Vessel-sealing capabilities were assessed via burst-pressure studies. The extent of thermal spread was measured after tissue fixation and hematoxylin and eosin staining.
Results:
Surgical clips/vascular staplers adequately controlled/sealed renal hilar vessels with burst pressures nearing 300 mm Hg. The Gyrus bipolar device reliably sealed and divided renal arteries
Conclusions:
The Gyrus PlasmaKinetic bipolar device is capable of reliably sealing/ dividing arteries as large as 6 mm, although we recommend restricting its use to vessels no larger than 5 mm in diameter to allow a safety margin. In addition, porcine renal veins of all sizes are adequately controlled. These sealed vessels are able to withstand pressures approaching 300 mm Hg. Thermal spread affects only the area surrounding the divided vessel. Further clinical studies are warranted.
