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Related Experiment Videos

Primary intranodal cellular angiolipoma.

Dmitry V Kazakov1, Ondrej Hes, Milan Hora

  • 1Sikl's Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic.

International Journal of Surgical Pathology
|March 1, 2005
PubMed
Summary
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Angiolipoma, a benign soft tissue tumor, can rarely occur within lymph nodes. This case highlights the importance of distinguishing lymph node angiolipoma from metastatic cancer.

Area of Science:

  • Pathology
  • Surgical Oncology
  • Vascular Tumors

Background:

  • Angiolipoma is a benign soft tissue tumor typically found in young males.
  • It commonly presents as painful subcutaneous nodules, particularly on the forearms.

Observation:

  • A case of angiolipoma developing within a lymph node is presented.
  • The lesion was found in a 67-year-old man post-prostatectomy and lymphadenectomy.
  • Gross examination revealed a suspicious lesion within an obturator lymph node.

Findings:

  • Microscopic analysis showed the lymph node largely replaced by mature adipose tissue.
  • The angiolipoma was well-demarcated, composed of small blood vessels with fibrin thrombi.
  • Focal areas showed increased cellularity and endothelial cell growth.

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Implications:

  • Primary angiolipoma in lymph nodes is rare and can be mistaken for metastatic adenocarcinoma.
  • Accurate diagnosis is crucial to avoid misinterpretation as malignancy.
  • This finding expands the differential diagnosis for lymph node lesions.