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Updated: Aug 19, 2026
Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
Published on: March 5, 2018
The South African bone marrow registry (SABMR) in 2004
Ernette D du Toit1, Veronica Borrill, Terry E-A Schlaphoff
1SABMR, Laboratory for Tissue Immunology, National Health Laboratory Service and University of Cape Town, Cape Town, South Africa.
Abstract:
Because of the presence of rare HLA antigens, particularly in patients of African ancestry, the SABMR was established in 1991. Currently approximately 20% of unique HLA types in the international database is from the SABMR. The SABMR donors now total approximately 45,000. Sixty-five South African patients have received matched unrelated donor transplants, 20 (30%) with a local donor. Most donors are from Caucasian background. To increase the genetic diversity of the SABMR donor pool, the policy is now to enrol more black and mixed ancestry donors.
