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[Eosinophilic esophagitis: 3 case reports].

Chrystèle Budin1, Florence Villard-Truc, Christine Rivet

  • 1Département de Pédiatrie, Unité d'Hépato-Gastroentérologie Pédiatrique, Hôpital Edouard Herriot, 69437 Lyon Cedex 03, France.

Gastroenterologie Clinique Et Biologique
|March 2, 2005
PubMed
Summary

Eosinophilic esophagitis, a rare condition involving eosinophil buildup in the esophagus, can present with unusual symptoms like dysphagia. Early diagnosis via biopsy is crucial, especially when food allergies are suspected in children.

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Area of Science:

  • Gastroenterology
  • Allergy Immunology
  • Pediatric Medicine

Background:

  • Eosinophilic esophagitis (EoE) is a rare immune-mediated esophageal disease.
  • It is characterized by eosinophilic infiltration of the esophageal mucosa, distinct from gastroesophageal reflux disease.
  • Food allergies are frequently implicated in the pathogenesis of EoE.

Observation:

  • This report details three pediatric cases of eosinophilic esophagitis.
  • The primary presenting symptom in these cases was dysphagia, with or without esophageal stricture.
  • The frequency of EoE may be underestimated, and its clinical presentation can be atypical.

Findings:

  • Oesogastroscopy with esophageal biopsy is the gold standard for diagnosing eosinophilic esophagitis.

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  • The investigation of potential food allergies is essential in patients diagnosed with EoE.
  • Prompt diagnosis and management are critical for pediatric patients.

    • Implications:

    • Increased awareness of eosinophilic esophagitis is needed among clinicians, particularly pediatricians.
    • Systematic investigation of food allergies should be standard practice for suspected EoE cases.
    • Early diagnosis and intervention can improve outcomes and prevent complications such as strictures.