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Updated: May 22, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood
Published on: April 28, 2016
Do peptides control their own birth and death?
1Institut de Pharmacologie, INSERM 716, Hôpital St Louis, 27 rue Juliette Dodu, 75010 Paris, France. robinfahraeus@yahoo.co.uk
Abstract:
The tumour suppressor protein p53 and the Epstein-Barr-virus-encoded Epstein-Barr virus nuclear antigen-1 (EBNA1) can regulate their own proteasomal degradation and mRNA translation - in effect, they mediate control of their own steady-state levels. A large fraction of mRNA-translation-initiation events does not give rise to functional proteins; so could this reflect a more widespread concept by which certain proteins that require tight control of expression use similar means of self-regulation?
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