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Multimodal Study of Murine Cardiovascular Remodeling: Four-Dimensional Ultrasound and Mass Spectrometry Imaging
Published on: January 10, 2025
Ultrasound imaging versus morphopathology in cardiovascular diseases. Coronary collateral circulation and
Giorgio Baroldi1, Riccardo Bigi, Lauro Cortigiani
1Institute of Clinical Physiology, National Research Council, Milan and Pisa, Italy. gbaroldi@tin.it
Insights
This review compares histopathological and imaging studies on human coronary collateral circulation. It highlights the role of collaterals in normal and diseased vessels, and summarizes echocardiography
Area of Science:
- Cardiovascular Research
- Medical Imaging
- Histopathology
Background:
- Coronary collateral circulation plays a crucial role in myocardial perfusion.
- Understanding collateral function is vital for managing ischemic heart disease.
Purpose of the Study:
- To compare histopathological findings with clinical imaging results for assessing coronary collateral circulation.
- To describe the morphological role of collaterals in coronary vessels.
- To summarize the current and future applications of echocardiography in evaluating collateral function.
Main Methods:
- Review of existing histopathological studies on coronary vessels.
- Analysis of clinical imaging studies evaluating collateral circulation.
- Summary of echocardiographic techniques and their application.
Main Results:
- Morphological studies reveal the significance of collaterals in both healthy and atherosclerotic coronary arteries.
- Clinical imaging provides functional assessment of collateral pathways.
- Echocardiography offers a non-invasive method for evaluating collateral circulation.
Conclusions:
- Histopathology and clinical imaging provide complementary information on coronary collateral circulation.
- Echocardiographic techniques show promise for future assessment of collateral function.
- Further research is needed to fully integrate these methods for improved patient outcomes.
Abstract:
This review article is aimed at comparing the results of histopathological and clinical imaging studies to assess coronary collateral circulation in humans. The role of collaterals, as emerging from morphological studies in both normal and atherosclerotic coronary vessels, is described; in addition, present role and future perpectives of echocardiographic techniques in assessing collateral circulation are briefly summarized.
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