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Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
Published on: September 14, 2019
[Cyclospora cayetanensis in patients with AIDS and chronic diarrhea]
Jorge Néstor Velásquez1, Silvana Carnevale, Marta Cabrera
1Sala 4, Hospital Municipal de Infecciosas "Dr Francisco J. Muñiz", Buenos Aires, Argentina. jorsil@overnet.com.ar
Abstract:
Cyclospora spp. is a protozoan parasite responsible for significant gastrointestinal disease in patients infected with the human immunodeficiency virus. We report the clinical features of two patients with chronic diarrhea and intestinal cyclosporosis caused by Cyclospora cayetanensis. The average value for CD4 count in these patients was lower than or equal to 100 cells/mm3. The oocysts were detected in smears from stool samples stained with modified acid-fast or safranin technique. Light microscopy revealed parasites in the enterocytes and these parasites were associated with villous atrophy. Cyclospora cayetanensis infection might be an important cause of diarrhea in patients with AIDS in Argentina.
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