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Updated: Aug 19, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
Tobacco, oral cancer, and treatment of dependence
Saman Warnakulasuriya1, Gay Sutherland, Crispian Scully
1Department of Oral Medicine and Pathology, Guy's, King's and St Thomas' School of Dentistry, WHO Collaborating Centre for Oral Cancer and Precancer, King's College London, Denmark Hill Campus, Caldecot Road, London SE5 9RW, UK. s.warne@kcl.ac.uk
Abstract:
Tobacco dependence is recognised as a life-threatening disorder with serious oral health consequences which responds to treatment in the form of behavioural support and medication. While cigarette smoking is the most hazardous and prevalent form of tobacco use in the west, consideration also needs to be given to other forms such as bidi smoking in India, reverse smoking by several rural populations and use of snuff and chewing tobacco. The evidence that the use of tobacco is the major risk factor for oral cancer and potentially malignant lesions of the mouth is clear. Counseling to quit smoking is not applied in a systematic or frequent manner to people presenting with potentially malignant lesions of the oral cavity. This review makes recommendations for interventions by health professionals to encourage and aid cessation of tobacco use as a part of prevention of oral cancer.
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