Evolution of human immunodeficiency virus under selection and weak recombination

I M Rouzine1, J M Coffin

  • 1School of Medicine, Tufts University, Boston, Massachusetts 02111, USA. irouzine@tufts.edu

Genetics
|March 4, 2005
PubMed
Summary

This study models drug resistance in antiretroviral therapy by analyzing beneficial allele accumulation. Partial depletion of HIV populations can suppress the emergence of drug-resistant strains.

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