Related Experiment Video
Updated: Sep 22, 2026
Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells
Published on: November 18, 2022
Hepatoprotective activity of the constituents in Swertia pseudochinensis
Jian-Chen Li1, Li Feng, Bao-Hui Sun
1Faculty of Pharmaceutical Sciences, Kumamoto University, Oe-honmachi, Kumamoto, Japan. 028p9062@pharm.stud.kumamoto-u.ac.jp
Abstract:
A new xanthone derivative was isolated together with other 13 known constituents from a Chinese natural medicine, Swertia pseudochinensis HARA. Their structures were determined based on the spectral and chemical evidences. Furthermore, respective hexane, ethyl acetate, 1-BuOH, MeOH and water extracts of S. pseudochinensis, and purified compounds were respectively evaluated for their hepatoprotective activities against hepatocyte injury induced by CCl4. All the extracts and isolated compounds exhibited significant hepatoprotective activities at a dose showing no hepatoxicity.
