The acceptance of three simultaneous vaccine injections recommended at 12 months of age

Related Experiment Video

Updated: Aug 19, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

Jeffrey N Hanna1, Ruth C Bullen, Debora E Andrews

  • 1Tropical Public Health Unit, Cairns, Queensland. Jeffrey_hanna@health.qld.gov.au

Communicable Diseases Intelligence Quarterly Report
|March 5, 2005
PubMed

Insights

Simultaneous vaccination with Meningococcal C conjugate vaccine (MenCCV), measles-mumps-rubella (MMR), and Haemophilus influenzae type b (Hib) vaccines is recommended. Non-simultaneous administration risks delayed or missed MenCCV doses in children.

Area of Science:

  • Pediatric Infectious Diseases
  • Vaccinology
  • Public Health

Background:

  • Meningococcal C conjugate vaccine (MenCCV) is recommended at 12 months alongside MMR and Hib vaccines.
  • Simultaneous vaccination aims to maximize coverage and timely protection.
  • North Queensland implemented MenCCV vaccination in January 2003.

Purpose of the Study:

  • To assess the uptake of MenCCV when co-administered with MMR and Hib vaccines.
  • To identify factors associated with non-simultaneous vaccination.
  • To evaluate the implications for future vaccination programs.

Main Methods:

  • Retrospective cohort study of 751 children born in North Queensland in January 2003.
  • Analysis of vaccination records for MenCCV, MMR, and Hib vaccines.
  • Comparison of median ages for MenCCV receipt based on co-administration status.

Main Results:

  • 83% of children received MenCCV simultaneously with MMR and Hib vaccines.
  • Of those not vaccinated simultaneously, 72% received MenCCV by 18 months.
  • Median age for simultaneous vaccination was 12.3 months versus 14.0 months for non-simultaneous vaccination.

Conclusions:

  • Non-simultaneous vaccination increases the risk of delayed or missed MenCCV doses.
  • Timely administration of MenCCV is crucial for optimal public health outcomes.
  • Findings have implications for the introduction of the universal infant pneumococcal vaccination program.

More Related Videos

Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches13:36

Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches

Published on: May 6, 2015

Consistent Delivery of Adeno-Associated Virus via Lateral Tail-Vein Injection in Adult Mice05:03

Consistent Delivery of Adeno-Associated Virus via Lateral Tail-Vein Injection in Adult Mice

Published on: August 23, 2024

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...