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[Left atrial thrombus. Its evolution with oral anticoagulation].

J A Sobrino1, J E Centeno, I Maté

  • 1Unidad Médico Quirúrgica de Cardiología, Hospital La Paz, Facultad de Medicina, Universidad Autónoma, Madrid.

Revista Espanola De Cardiologia
|March 1, 1992
PubMed
Summary

Patients with left atrial thrombi face a high risk of arterial embolism. However, oral anticoagulation therapy effectively resolves these thrombi in most cases, offering significant therapeutic benefits.

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Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Left atrial thrombi are a significant concern in patients with atrial fibrillation.
  • Associated conditions include mitral valve disease and bioprosthetic valves.
  • A history of arterial embolism increases patient risk.

Purpose of the Study:

  • To investigate the resolution of left atrial thrombi with oral anticoagulation.
  • To assess the risk of arterial embolism in affected patients.
  • To evaluate therapeutic implications of anticoagulation.

Main Methods:

  • Two-dimensional echocardiography was used for diagnosis.
  • Patients received oral anticoagulation with coumadin.
  • Follow-up included clinical assessment and echocardiography.

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Main Results:

  • Left atrial thrombi resolved in 72% of patients and reduced in size in one patient.
  • Four patients underwent successful percutaneous mitral valvuloplasty after thrombi resolution.
  • One patient experienced a cerebral embolism without lasting effects.

Conclusions:

  • Left atrial thrombi are linked to a high risk of arterial embolism.
  • Oral anticoagulation is highly effective in resolving left atrial thrombi, indicating its crucial therapeutic role.