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[Sweet's syndrome in a child].

K Laïssaoui1, S Amal, O Hocar

  • 1Service de Dermatologie, CHU Mohammed VI, Marrakech, Maroc. karima_doc@hotmail.com

Annales De Dermatologie Et De Venereologie
|March 5, 2005
PubMed
Summary
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Sweet's syndrome, a rare pediatric condition, can manifest in infants. Early corticosteroid treatment shows promise for managing this inflammatory disorder.

Area of Science:

  • Pediatric Dermatology
  • Hematology
  • Immunology

Background:

  • Sweet's syndrome, first described in 1964, is predominantly diagnosed in adults.
  • Its occurrence in pediatric populations, particularly infants, is exceptionally rare.

Observation:

  • A 23-month-old boy presented with characteristic skin lesions including papular, edematous annular plaques with surrounding vesicles and bullae.
  • Initial laboratory findings revealed neutrophilic hyperleukocytosis, anemia, and an inflammatory syndrome.

Findings:

  • The patient showed a significant clinical response to oral corticosteroids at a dosage of 2 mg/kg/d.
  • Despite initial improvement, the infant later developed cervical adenopathies and hepatomegaly, with subsequent myelograms remaining normal.

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Implications:

  • This case highlights the rarity of Sweet's syndrome in infants and the importance of considering hematologic malignancies.
  • Systemic corticosteroid therapy is established as the primary treatment modality for Sweet's syndrome.