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Updated: Aug 16, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
A case with widespread cutaneous metastases of unknown primary origin: grave prognostic finding in cancer
Rafet Koca1, Yucel Ustundag, Eksal Kargi
1Department of Dermatology, Zonguldak Karaelmas University, School of Medicine, Turkey. rafetkoca@karaelmas.edu.tr
Abstract:
We present a 52-year-old man with widespread cutaneous metastases (CMs) of unknown primary origin. Although we performed many of the investigations, we could not find out a primary origin of malignancy. There are no practical algorithms to identify the primary of cutaneous metastatic tumors of unknown origin. An algorithm in cancer patients with CMs seems to be needed to manipulate such cases. We believe that more reports related with this issue must be published to form an algorithm in such cases.
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