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Primary (idiopathic) cold urticaria and cholinergic urticaria
1Ronald O. Perelman Department of Dermatology, New York University, USA.
Dermatology Online Journal
|March 8, 2005
Summary
Cold urticaria causes hives and swelling after cold exposure. Antihistamines are a common treatment, with other options available for severe cases.
Area of Science:
- Dermatology
- Immunology
Background:
- Cold urticaria is a physical urticaria triggered by cold stimuli.
- It can manifest as hives and angioedema.
- Causes may be idiopathic or secondary to other conditions.
Observation:
- A 76-year-old male with a history of cold sensitivity experienced wheals upon ice cube application.
- This case illustrates a typical presentation of cold urticaria.
Findings:
- Cold urticaria is characterized by urticaria and angioedema following cold exposure.
- Primary cold urticaria often responds to antihistamines.
Implications:
- Refractory cases may benefit from alternative treatments like ketotifen, doxantrazole, zafirlukast, cyclosporine, or cold-tolerance induction.
- Understanding treatment options is crucial for managing cold urticaria effectively.