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Multiple eruptive keratoacanthomas, de novo.

¹Ronald O. Perelman Department of Dermatology, New York University, USA.

Dermatology Online Journal

|March 8, 2005

Summary

A rare case of multiple eruptive keratoacanthomas in an elderly man showed resistance to topical imiquimod treatment. This highlights the need to explore alternative therapeutic strategies for this uncommon skin condition.

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Area of Science:

Dermatology
Oncology

Background:

Keratoacanthomas are common skin tumors, but multiple eruptive keratoacanthomas are rare.
This condition presents as a sudden eruption of numerous lesions, often on sun-exposed areas.

Observation:

An 89-year-old male presented with a sudden onset of multiple erythematous papules and nodules on his lower extremities.
Skin biopsy confirmed the diagnosis of keratoacanthoma.

Findings:

Topical imiquimod cream, applied for 3 months, was ineffective in resolving the keratoacanthomas.
The case underscores the potential for treatment resistance in multiple eruptive keratoacanthomas.

Implications:

This case necessitates a review of various clinical subtypes, histological features, and treatment options for multiple eruptive keratoacanthomas.
Further research into effective treatment modalities for this rare condition is warranted.

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