Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biofilms and the plasmid maintenance question.

Mudassar Imran1, Don Jones, Hal Smith

  • 1Department of Mathematics and Statistics, Arizona State University, Tempe, AZ 85287, USA.

Mathematical Biosciences
|March 8, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

scRNA-seq and scATAC-seq reveal dual transcriptional and translational regulation of fiber cells in Upland and Pima cotton.

Plant physiology·2026
Same author

CottonGen 2025: a knowledgebase for cotton genomics, genetics, and breeding research.

Genetics·2026
Same author

Semantic-aware reinforcement and ensemble learning for signal management and anomaly detection in IoT systems.

Scientific reports·2025
Same author

Nonlinear Stochastic Dynamics of the Intermediate Dispersive Velocity Equation with Soliton Stability and Chaos.

Entropy (Basel, Switzerland)·2025
Same author

Enhanced medical image segmentation using novel level set evolution and efficient optimization.

Scientific reports·2025
Same author

An exploration of the (3+1)-dimensional negative order KdV-CBS model: Wave solutions, Bäcklund transformation, and complexiton dynamics.

PloS one·2024

A conjugative plasmid that enhances bacterial biofilm formation can persist in a population, even with slower growth and plasmid loss. This suggests biofilm ability can overcome negative fitness costs for plasmid stability.

Area of Science:

  • Microbiology
  • Mathematical Biology
  • Genetics

Background:

  • Conjugative plasmids can spread traits within bacterial populations.
  • Biofilm formation is a key bacterial adaptation.
  • Plasmid carriage can impose fitness costs on host bacteria.

Purpose of the Study:

  • To investigate if enhanced biofilm formation can compensate for negative fitness effects of a conjugative plasmid.
  • To determine conditions under which such plasmids persist in bacterial populations.

Main Methods:

  • Mathematical modeling of bacterial population dynamics.
  • Analysis in chemostat and plug flow reactor environments.
  • Derivation of explicit conditions for plasmid persistence.

Related Experiment Videos

Main Results:

  • Conditions were derived where enhanced biofilm formation ensures plasmid persistence.
  • Mathematical model demonstrates persistence despite reduced growth rate and plasmid loss.
  • Numerical simulations validated the theoretical findings.

Conclusions:

  • Enhanced biofilm formation can be a strong selective advantage for conjugative plasmids.
  • Plasmid-mediated biofilm enhancement can overcome segregative loss and growth rate reduction.
  • This mechanism is crucial for understanding plasmid dynamics in microbial communities.