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Published on: December 27, 2016
Biofilms and the plasmid maintenance question
Mudassar Imran1, Don Jones, Hal Smith
1Department of Mathematics and Statistics, Arizona State University, Tempe, AZ 85287, USA.
Abstract:
Can a conjugative plasmid encoding enhanced biofilm forming abilities for its bacterial host facilitate the persistence of the plasmid in a bacterial population despite conferring diminished growth rate and segregative plasmid loss on its bearers? We construct a mathematical model in a chemostat and in a plug flow environment to answer this question. Explicit conditions for an affirmative answer are derived. Numerical simulations support the conclusion.
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