Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Amblyopia characterization, treatment, and prophylaxis.

Kurt Simons1

  • 1Pediatric Vision Laboratory, Krieger Children's Eye Center, Wilmer Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-9028, USA.

Survey of Ophthalmology
|March 8, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A PC-based shutter glasses controller for visual stimulation using multithreading in LabWindows/CVI.

Computer methods and programs in biomedicine·2017
Same author

Laterality of amblyopia.

American journal of ophthalmology·2010
Same author

Old age and the functional consequences of amblyopia.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2008
Same author

Hyperopia, accommodative dysfunction and reading.

Binocular vision & strabismus quarterly·2004
Same journal

Trends in pediatric uveitis: A systematic review and meta-epidemiological investigation of geographic, economic, and climate factors.

Survey of ophthalmology·2026
Same journal

Efficacy and safety of different intraocular therapies for non-infectious uveitis: A network meta-analysis.

Survey of ophthalmology·2026
Same journal

Macular telangiectasia masqueraders.

Survey of ophthalmology·2026
Same journal

Utilization of anterior segment optical coherence tomography in childhood glaucoma: A systematic review.

Survey of ophthalmology·2026
Same journal

Peripapillary pachychoroid syndrome: Clinical and imaging features, diagnostic differentiation and therapeutic strategies.

Survey of ophthalmology·2026
Same journal

Prognostic factors and postoperative outcomes in pediatric cataract patients: A systematic review and meta-analysis.

Survey of ophthalmology·2026
See all related articles

Amblyopia, or lazy eye, affects 1.6-3.6% of children and is more complex than initially thought. Early detection and treatment, potentially through cost-effective photoscreening, are crucial for better outcomes in amblyopia management.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Vision Science

Background:

  • Amblyopia (lazy eye) affects 1.6-3.6% of the population, disproportionately impacting underserved communities.
  • The condition involves sub-clinical deficits in the better-seeing eye and more extensive functional limitations than previously understood.
  • Current screening and treatment methods for amblyopia face cost-effectiveness challenges.

Purpose of the Study:

  • To review the complexities of amblyopia, including its prevalence, functional impact, and the efficacy of various screening and treatment modalities.
  • To identify challenges in amblyopia literature interpretation and explore potential improvements in detection and treatment strategies.
  • To evaluate the effectiveness of different interventions, such as refractive correction, penalization, occlusion, and novel medical treatments.

Related Experiment Videos

Main Methods:

  • Literature review of amblyopia screening and treatment studies.
  • Analysis of factors influencing treatment outcomes, including age of onset, visual acuity, treatment type, duration, and compliance.
  • Evaluation of emerging screening technologies like cycloplegic photoscreening and multivariate screening methods.

Main Results:

  • Refractive correction alone can treat anisometropic amblyopia; atropine penalization is as effective as occlusion for moderate cases.
  • Treatment success rates range from 63-83%, influenced by initial visual acuity, amblyopia type, treatment efficacy, duration, and compliance.
  • Early infant refractive correction reduces esotropia and amblyopia incidence; early detection (under 2-3 years) is critical.

Conclusions:

  • Amblyopia management requires accurate initial measurements, adequate refractive correction, and long-term follow-up.
  • Novel approaches like early photoscreening and medical treatments (e.g., Cytidin-5'-diphosphocholine) show promise for improved amblyopia care.
  • Multivariate screening and early interventions, including infant refractive correction, may enhance detection and reduce the prevalence of amblyopia and related conditions like esotropia.