Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

PSIbase: a database of Protein Structural Interactome map (PSIMAP).

Sungsam Gong1, Giseok Yoon, Insoo Jang

  • 1Biomatics Lab, Department of BioSystems, KAIST, Daejeon, Korea.

Bioinformatics (Oxford, England)
|March 8, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Programmable one-pot polymerase-mediated DNA synthesis via temperature control.

Nature communications·2026
Same author

Gut microbiota transfer from autoimmune dry eye mice imprints stereotypic B cell receptor repertoires in the lacrimal gland and induces disease.

Frontiers in immunology·2026
Same author

Cardiovascular Health Score, Social Network Size, and All-Cause Mortality in a Korean Prospective Cohort.

European journal of preventive cardiology·2026
Same author

Development and comparison of evaluation metrics for batch correction reveals performance differences.

Bioinformatics advances·2026
Same author

MetaCancerDB: a database of site-specific RNA-miRNA correlations in cancer metastasis.

Database : the journal of biological databases and curation·2026
Same author

On the state of protein function prediction: a report on the fourth CAFA challenge.

bioRxiv : the preprint server for biology·2026

Protein Structural Interactome map (PSIMAP) provides a global view of protein interactions using structural data. PSIbase offers a database and tools to explore these protein domain interactions and identify potential partners.

Area of Science:

  • Structural biology
  • Bioinformatics
  • Computational biology

Background:

  • Protein Structural Interactome map (PSIMAP) analyzes known Protein Data Bank structures.
  • It focuses on domain-domain and protein-protein interactions.
  • Available at http://psimap.org and http://psibase.kaist.ac.kr/.

Purpose of the Study:

  • To create a comprehensive map of protein structural interactions.
  • To develop a database (PSIbase) for accessing and visualizing this interaction data.
  • To provide tools for identifying potential protein interaction partners.

Main Methods:

  • Utilizes the PSIMAP algorithm to calculate interactions.
  • Employs Euclidean distance to determine interactions between structural domains.

Related Experiment Videos

  • Integrates domain assignment, navigation, and visualization tools.

    • Main Results:

    • Generated a global interaction map of protein domains.
    • Established PSIbase as a resource for protein structural interaction information.
    • Enabled retrieval of potential interaction partners based on homology.

    Conclusions:

    • PSIMAP and PSIbase offer valuable resources for understanding protein structure-based interactions.
    • The tools facilitate the discovery of novel protein interaction networks.
    • Facilitates research in structural biology and drug discovery.