Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Placebo.

H J McQuay1, R A Moore

  • 1Pain Research, Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Oxford OX3 7LJ, UK. henry.mcquay@pru.ox.ac.uk

Postgraduate Medical Journal
|March 8, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy.

BMC anesthesiology·2017
Same author

European Pain Federation position paper on appropriate opioid use in chronic pain management.

European journal of pain (London, England)·2016
Same author

Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy.

BMC anesthesiology·2016
Same author

Randomized clinical trial of dexketoprofen/tramadol 25 mg/75 mg in moderate-to-severe pain after total hip arthroplasty.

British journal of anaesthesia·2016
Same author

A conservative method of testing whether combination analgesics produce additive or synergistic effects using evidence from acute pain and migraine.

European journal of pain (London, England)·2012
Same author

End-to-end military pain management.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2010
Same journal

Dapagliflozin-induced anaphylactic shock.

Postgraduate medical journal·2026
Same journal

Comparative efficacy of Janus kinase inhibitors in severe alopecia areata: a network meta-analysis based on randomized controlled trials.

Postgraduate medical journal·2026
Same journal

Two cases of toxic epidermal necrolysis with severe ocular involvement treated with adjunctive tofacitinib.

Postgraduate medical journal·2026
Same journal

Diastolic dysfunction and diabetes: the DIADAD study-a retrospective cohort study from Liverpool.

Postgraduate medical journal·2026
Same journal

Care, cash, and proof: forensic accountability for war-related starvation.

Postgraduate medical journal·2026
Same journal

Response to traumatic injuries in polo players in England.

Postgraduate medical journal·2026
See all related articles

Placebos are inert treatments used in clinical trials, with their effects and mechanisms explored. The article also discusses the ethical considerations of using placebos in research and clinical practice.

Area of Science:

  • Pharmacology
  • Clinical Research
  • Medical Ethics

Background:

  • The term "placebo" has varied interpretations.
  • Placebos are inert substances or treatments given to patients as if they were active therapies.
  • Understanding placebo effects is crucial in medical research and practice.

Purpose of the Study:

  • To define the technical use of placebos in clinical trials.
  • To examine the extent and mechanisms of the placebo response.
  • To discuss the ethical implications of placebo use in research and clinical settings.

Main Methods:

  • Literature review on placebo definitions and uses.
  • Analysis of placebo response extent in clinical trials.
  • Exploration of placebo mechanisms.
Keywords:
Biomedical and Behavioral ResearchHealth Care and Public Health

Related Experiment Videos

  • Ethical analysis of placebo use in research and practice.

    • Main Results:

    • Placebo response varies significantly across different conditions and individuals.
    • Multiple mechanisms contribute to placebo effects, including conditioning, expectation, and neurobiological pathways.
    • Ethical considerations differ between placebo use in research versus clinical practice.

    Conclusions:

    • A comprehensive understanding of placebo effects is essential for accurate clinical trial interpretation.
    • The ethical application of placebos requires careful consideration of patient welfare and informed consent.
    • Further research into placebo mechanisms may offer insights into therapeutic interventions.