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Updated: Feb 8, 2026

Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes
Published on: January 30, 2019
Structural manifestations of the cheletropic reaction
Goh Yit Wooi1, Jonathan M White
1School of Chemistry, University of Melbourne, Parkville, VIC 3010, Melbourne, Australia.
Abstract:
Examination of selected cyclopentenone derivatives which are fixed into the boat conformation reveals structural deviations from "normal" C-C(O) and C=O bond distances consistent with the early stages of the cheletropic extrusion of carbon monoxide.
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