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Perforated appendicitis in a child with Henoch-Schönlein purpura
Bryce A Binstadt1, Eric W Fleegler
1Rheumatology Program, Division of Immunology, Children's Hospital Boston, Boston, MA 02115, USA. bryce.binstadt@childrens.harvard.edu
Insights
Henoch-Schönlein purpura (HSP) can present with abdominal pain, mimicking surgical emergencies. This case highlights appendicitis occurring with an established HSP rash, emphasizing the need for careful diagnosis.
Area of Science:
- Pediatric Rheumatology
- Pediatric Surgery
Background:
- Henoch-Schönlein purpura (HSP) is a common childhood vasculitis.
- Abdominal pain is a frequent symptom, often prompting evaluation for intussusception.
- Appendicitis is a rare complication, typically preceding rash onset in prior reports.
Observation:
- This report details the first case of appendicitis developing in a child with an established HSP rash.
- The patient presented with symptoms suggestive of appendicitis alongside the characteristic purpuric rash.
- This case also represents the first documented instance of perforated appendicitis in the context of HSP.
Findings:
- Appendicitis can occur concurrently with the established rash of Henoch-Schönlein purpura.
- Perforated appendicitis is a potential, albeit rare, complication in children with HSP.
- Distinguishing appendicitis from other abdominal pain causes in HSP requires vigilance.
Implications:
- Clinical vigilance and serial examinations are crucial for accurate diagnosis in HSP patients with abdominal pain.
- Diagnostic imaging, including ultrasonography, aids in differentiating surgical conditions from HSP symptoms.
- Avoiding unnecessary surgical interventions in suspected appendicitis cases within the HSP spectrum is important.
Abstract:
Henoch-Schönlein purpura (HSP) is a common childhood vasculitis. Abdominal pain is a common feature of HSP, often leading to surgical consultation for evaluation of possible intussusception. Appendicitis is a rare complication of HSP, and in each of the 3 reported cases, appendectomy preceded the appearance of the purpuric rash. More often, unnecessary laparotomies are performed on patients in whom appendicitis is suspected, but who subsequently develop the characteristic purpura. This is the first reported case of appendicitis developing in a patient with the established HSP rash. This case is also the first report of perforated appendicitis in HSP. Clinical vigilance and serial physical and ultrasonographic examinations are needed to detect conditions necessitating surgery in patients with HSP.
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