Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antibiotic-associated neutropenia.

G S Walbroehl1, P G John

  • 1Wright State University School of Medicine, Dayton, Ohio.

American Family Physician
|May 1, 1992
PubMed
Summary

Drug-induced neutropenia, often linked to semisynthetic penicillins, is a serious side effect. Discontinuing the medication typically resolves this condition, improving white blood cell counts.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insomnia.

American family physician·1999
Same author

Recognition and treatment of obsessive-compulsive disorder.

American family physician·1998
Same author

Application of a rapid automated immunosensor for the detection of Staphylococcus aureus enterotoxin B in cream.

International journal of food microbiology·1997
Same author

Pulmonary hyalinizing granuloma: an unusual association with multiple sclerosis.

Southern medical journal·1995
Same author

Homosexuality: is it a choice?

American family physician·1994
Same author

Myocardial infarction and position during sexual intercourse.

American family physician·1994

Area of Science:

  • Pharmacology
  • Hematology
  • Toxicology

Background:

  • Drug-induced neutropenia is a rare but significant adverse effect of various medications.
  • Antibiotics, particularly semisynthetic penicillins, are frequently implicated in its development.

Observation:

  • Neutropenia commonly manifests after two weeks of continuous semisynthetic penicillin therapy.
  • The condition involves a decrease in neutrophils, a type of white blood cell.

Findings:

  • The etiology is hypothesized to involve either a hypersensitivity immune response or direct toxicity to bone marrow precursors.
  • Most cases of drug-induced neutropenia resolve upon cessation of the causative agent.

Implications:

  • Awareness of drug-induced neutropenia is crucial for clinicians managing patients on relevant medications.
  • Prompt identification and discontinuation of offending drugs can prevent severe complications and facilitate recovery.

Related Experiment Videos