Efficacy of platelet gel in reconstructive bone surgery
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Updated: Aug 19, 2026

Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
Published on: September 29, 2015
Massimo Franchini1, Paolo Dupplicato, Isabella Ferro
1Transfusion Service, Hospital of Verona, Verona, Italy.
Abstract:
Autologous platelet concentrate and cryoprecipitate, mixed to obtain a gel, have been successful in various operations, primarily oral and maxillofacial surgery. This study assessed the use of platelet gel in 19 patients undergoing 22 reconstructive bone surgical procedures. After a median follow-up of 12.9 months, improved osteoblastic reaction and reconstruction of physiologic bone structure was observed in all patients with no adverse reactions. These findings confirm the osteoinductive property of platelet gel in reconstructive bone surgery.
