Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tongue disease in advanced AIDS.

P R de Faria1, P A Vargas, P H N Saldiva

  • 1Department of Oral Pathology, Dental School of Piracicaba-UNICAMP, Piracicaba-SP, Brazil.

Oral Diseases
|March 9, 2005
PubMed
Summary

The tongue frequently shows reactive, infectious, and concurrent lesions in patients with acquired immunodeficiency syndrome (AIDS). Histological analysis of 92 autopsied AIDS patients revealed alterations in 75%, with hairy leukoplakia and candidosis being most common.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

IL-6 and TGF-β1 as biomarkers of schistosomiasis-associated pulmonary hypertension in a murine model.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2026
Same author

Fragrances as a trigger of immune responses in different environments.

Toxicology in vitro : an international journal published in association with BIBRA·2023
Same author

Efficient quantitative assessment of robot swarms: coverage and targeting Lévy strategies.

Bioinspiration & biomimetics·2022
Same author

Evaluation of the screw tent-pole technique for the repair of anterior maxilla width defects: a prospective, randomized, split-mouth study.

International journal of oral and maxillofacial surgery·2020
Same author

Oral vesiculobullous lesions as an early sign of COVID-19: immunohistochemical detection of SARS-CoV-2 spike protein.

The British journal of dermatology·2020
Same author

PI3K/AKT/mTOR pathway activation in actinic cheilitis and lip squamous cell carcinomas.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020

Area of Science:

  • Oral pathology
  • Infectious diseases
  • Immunology

Background:

  • Acquired immunodeficiency syndrome (AIDS) significantly impacts oral health.
  • The tongue is a common site for opportunistic infections and lesions in advanced HIV disease.

Purpose of the Study:

  • To investigate the spectrum of histological alterations in the tongues of autopsied patients who died with AIDS.
  • To identify the prevalence and types of oral lesions associated with end-stage AIDS.

Main Methods:

  • Autopsy examination of tongues from 92 patients with AIDS.
  • Macroscopical and histological analysis using various staining techniques (H&E, Gomori-Grocott, Ziehl-Neelsen, PAS, Brow-Hopps, Mucicarmine).
  • Correlation with clinical data including CD4 cell count.

Related Experiment Videos

Main Results:

  • Histological alterations were observed in 75% of the cases.
  • Most frequent lesions included hairy leukoplakia (42%), candidosis (31%), and chronic glossitis (29%).
  • Common co-occurring lesions were hairy leukoplakia with candidosis (13 cases).

Conclusions:

  • The tongue serves as a significant site for reactive, infectious, and concurrent lesions in end-stage AIDS.
  • These findings highlight the importance of oral examination in managing AIDS patients.
  • Understanding these oral manifestations aids in diagnosis and patient care.