Tacrolimus ointment for the treatment of severe facial plaque psoriasis
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Updated: Aug 5, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
E B M Kroft1, A Erceg, K Maimets
1Department of Dermatology, University Medical Centre St Radboud, PO Box 9101, 6500 HB Nijmegen, the Netherlands. i.kroft@derma.umcn.nl
Abstract:
Recently, tacrolimus ointment has proved to be effective and well tolerated in patients with facial psoriasis. A few months ago we had the opportunity to treat a patient with tacrolimus ointment who had severe and recalcitrant plaque psoriasis of the face. This present case illustrates the impressive improvement of facial plaque psoriasis following 5 months of treatment with tacrolimus 0.1% ointment twice a day. Significant improvement of facial plaque psoriasis was seen after 1 month and complete clearance after 5 months of therapy. Based on the available literature and illustrated by the present case we may conclude that tacrolimus ointment 0.1% can be recommended as a first-line treatment for facial psoriasis.
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