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West Nile virus in Morocco, 2003.

Isabelle Schuffenecker1, Christophe N Peyrefitte, Mohammed el Harrak

  • 1Centre de Référence des Arbovirus, Institut Pasteur, 21 Ave Tony Garnier, 69365 Lyon cedex 07, France. schuffenecker@cervi-lyon.inserm.fr

Emerging Infectious Diseases
|March 9, 2005
PubMed
Summary

West Nile virus (WNV) reemerged in Morocco in 2003, causing an equine outbreak. Phylogenetic analysis revealed Moroccan WNV strains are closely related to those in the western Mediterranean basin.

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Area of Science:

  • Veterinary Virology
  • Epidemiology
  • Molecular Biology

Background:

  • West Nile virus (WNV) poses a significant threat to equine health.
  • Morocco experienced a notable WNV outbreak in horses in 2003.

Purpose of the Study:

  • To characterize the WNV strain responsible for the 2003 Moroccan equine outbreak.
  • To determine the phylogenetic relationship of Moroccan WNV strains to other global strains.

Main Methods:

  • Complete genome sequencing of an isolated WNV strain from equine brain biopsy.
  • Phylogenetic analysis of WNV genetic sequences.

Main Results:

  • The WNV strain from the 2003 Moroccan outbreak was fully sequenced.
  • Moroccan WNV strains from 1996 and 2003 outbreaks showed close genetic relatedness to strains from the western Mediterranean basin.

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Conclusions:

  • The 2003 WNV outbreak in Morocco involved a strain genetically linked to those circulating in the western Mediterranean.
  • Ongoing surveillance and phylogenetic studies are crucial for understanding WNV emergence and spread in equine populations.