Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Controlling inflammation: a fat chance?

Roderick J Flower1, Mauro Perretti

  • 1The William Harvey Research Institute, London EC1M 6BQ, UK. r.j.flower@qmul.ac.uk

The Journal of Experimental Medicine
|March 9, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: IkB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD.

Journal of the American Society of Nephrology : JASN·2026
Same author

The anti-inflammatory efficacy of melanocortin drugs is influenced by genetic variation at MC1R.

Scientific reports·2026
Same author

Interleukin-6 blockade modulates monocyte recruitment to protect against diastolic dysfunction associated with inflammatory arthritis.

Arthritis research & therapy·2026
Same author

Resolution Pharmacology: State-of-the-art and therapeutic landscape.

Pharmacological reviews·2025
Same author

The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis.

Arthritis research & therapy·2025
Same author

Comparative Assessment of Whole Organ Tissue Processing Methods for the Isolation of Extracellular Vesicles From Intact Organs.

Journal of extracellular vesicles·2025
Same journal

Retraction: In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation.

The Journal of experimental medicine·2026
Same journal

Intravesical mesothelin-based CAR T cells targeting MUC16 effectively control bladder cancer in preclinical models.

The Journal of experimental medicine·2026
Same journal

Flawed translation triggers oncogenic B-T cell communication.

The Journal of experimental medicine·2026
Same journal

Correction: LCK'ed in: Inborn errors of immunity in LCK reveal how TCR signaling is calibrated.

The Journal of experimental medicine·2026
Same journal

Mechanobiology of inflammation: Pulling the strings of innate immunity.

The Journal of experimental medicine·2026
Same journal

Bile acid retention in efferocytic macrophages shapes their inflammatory status during cholangitis.

The Journal of experimental medicine·2026
See all related articles

Resolvin E1, an endogenous compound, inhibits inflammation, supporting fish oil benefits. Aspirin

Area of Science:

  • Biochemistry
  • Immunology
  • Pharmacology

Background:

  • Inflammation is a vital defense mechanism.
  • Dysregulated inflammation can harm the host.
  • Endogenous pathways can counteract inflammation.

Purpose of the Study:

  • To investigate the role of resolvin E1 in regulating inflammation.
  • To explore the implications for fish oil supplementation.
  • To examine aspirin's pharmacological effects.

Main Methods:

  • Experimental evidence was gathered.
  • The effects of resolvin E1 were analyzed.
  • Pharmacological actions were studied.

Main Results:

  • Resolvin E1 was identified as an endogenous inhibitor of inflammation.

Related Experiment Videos

  • Findings support the benefits of fish oil dietary supplementation.
  • An unexpected pharmacological action of aspirin was observed.

    • Conclusions:

    • Resolvin E1 actively counterregulates inflammation.
    • Dietary fish oils may offer therapeutic anti-inflammatory benefits.
    • Aspirin exhibits novel pharmacological properties relevant to inflammation.