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Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots
Published on: June 2, 2015
Preparation and characterization of an electrodeposited calcium phosphate coating associated with a calcium alginate
R Hurteaux1, H Benhayoune, F Edwards-Levy
1INSERM-ERM 0203, Interfaces Biomatériaux-Tissus Hôtes, IFR 53, Université de Reims, Champagne-Ardenne 1, rue du Maréchal Juin, F-51095, Reims Cedex, France. reynald.hurteaux@univ-reims.fr
Abstract:
A new way of optimizing osteoconduction of biomaterials is to bring to them biological properties. In this work, we associated a novel release system with an electrodeposited calcium phosphate (CaP) coated titanium alloy Ti6Al4V. The characterization of this material was performed by means of light microscopy, scanning electron microscopy (SEM), scanning transmission electron microscopy (STEM) and X-ray energy dispersive spectroscopy (EDXS). The electrodeposited CaP coating was a tricalcium phosphate, and the release system was composed of microcapsules entrapped in an alginate film. We observed that the alginate matrix had a close contact with the coating. An intermediate layer containing calcium and phosphorus appeared at the interface between the alginate matrix and the CaP coating. These results allowed us to conclude that the association of two techniques, i.e. electrodeposition followed by deposition of a calcium alginate matrix, led to the elaboration of a new biomaterial.
