Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clostridium difficile causing acute renal failure: case presentation and review.

Jasmin Arrich1, Gottfried-H Sodeck, Gurkan Sengolge

  • 1Department of Emergency Medicine, Medical University Vienna, General Hospital, Wahringer Gurtel 18-20, A-1090, Austria.

World Journal of Gastroenterology
|March 9, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Saddle pulmonary embolism detected by transthoracic echocardiography-a case report.

Wiener klinische Wochenschrift·2026
Same author

Pediatric non-traumatic out-of-hospital cardiac arrest in a high-resource metropolitan area: epidemiology and outcomes.

BMC emergency medicine·2026
Same author

Clinical Determinants of Urinary Podocyte Biomarkers and Their Feasibility in Paraprotein-Related Kidney Disease.

Diagnostics (Basel, Switzerland)·2026
Same author

Near-infrared spectroscopy (NIRS) during and after cardiopulmonary resuscitation: A systematic review and meta-analysis.

Australian critical care : official journal of the Confederation of Australian Critical Care Nurses·2026
Same author

When controls are healthy: the difficulty of testing neuroprotection in low-injury models.

Intensive care medicine experimental·2026
Same author

Prevention of burnout syndrome in physicians: a systematic review and meta-analysis.

Wiener klinische Wochenschrift·2025

Clostridium difficile-associated diarrhea can lead to acute renal failure, particularly in the elderly. Prompt treatment of C. difficile infection and supportive care for kidney function are crucial for recovery.

Area of Science:

  • Infectious Diseases
  • Nephrology
  • Gastroenterology

Background:

  • Clostridium difficile infection (CDI) is a common nosocomial infection.
  • Asymptomatic carriers of C. difficile exist in up to 5% of the general population.
  • Antibiotics like ampicillin, cephalosporins, and clindamycin are frequently linked to CDI.

Purpose of the Study:

  • To investigate the association between Clostridium difficile-associated diarrhea (CDAD) and acute renal failure (ARF).
  • To report a case of CDAD complicated by ARF and review existing literature.

Main Methods:

  • A case report of an 82-year-old patient with CDAD and ARF.
  • Systematic review of literature to identify links between CDAD and ARF.

Main Results:

Related Experiment Videos

  • The patient experienced rapid improvement in both diarrhea and ARF after discontinuation of the offending antibiotic and symptomatic therapy.
  • Volume depletion was the likely cause of ARF in this patient.
  • Experimental studies suggest C. difficile toxins may directly impact renal tubule cells.

Conclusions:

  • CDAD can be a complication leading to ARF, especially in elderly patients.
  • Early diagnosis and prompt, supportive treatment, including antibiotics, are vital to reduce mortality.
  • Management should focus on addressing volume depletion and specific C. difficile treatment.