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Related Experiment Videos

[Anaphylactic reaction after Fe-injection].

R Fiechter1, M Batschwaroff, D Conen

  • 1Medizinische Klinik, Kantonsspital Aarau.

Praxis
|March 10, 2005
PubMed
Summary
This summary is machine-generated.

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An 84-year-old patient experienced anaphylaxis after receiving an intravenous iron injection intended for intramuscular use. This highlights the risks of incorrect iron formulation administration and the importance of proper administration routes.

Area of Science:

  • Clinical Medicine
  • Pharmacology
  • Anesthesiology

Background:

  • Iron deficiency anemia is common, especially in the elderly.
  • Intravenous iron formulations are used when oral iron is ineffective or not tolerated.
  • Correct administration routes are crucial for patient safety.

Observation:

  • An 84-year-old female developed anaphylaxis following an intravenous iron injection.
  • The patient was being treated for iron deficiency anemia.
  • The administered iron formulation (iron (III) hydroxide dextran complex) was intended for intramuscular use, not intravenous.

Findings:

  • The anaphylactic reaction was linked to the incorrect administration of an iron dextran complex intravenously.
  • The patient also experienced an acute anteroseptal myocardial event, managed with cardiac medication.

Related Experiment Videos

  • Mild renal insufficiency may have contributed to the patient's hemoglobin level of 101 g/L.

    • Implications:

    • This case underscores the critical importance of using the correct iron formulation and administration route to prevent adverse events.
    • Oral iron administration should be preferred unless an iron absorption disorder is confirmed.
    • Parenteral iron saccharate complex should only be used intravenously after a pathological oral iron load test.