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Functional capacity in severe chronic obstructive pulmonary disease.

Deniz Inal-Ince1, Sema Savci, Lutfi Coplu

  • 1School of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.

Saudi Medical Journal
|March 10, 2005
PubMed
Summary

Patients with severe chronic obstructive pulmonary disease (COPD) exhibit significantly reduced functional capacity compared to healthy individuals. The 6-minute walk test (6MWT) effectively measures this impairment, correlating with lung function and breathlessness levels.

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Area of Science:

  • Pulmonary Medicine
  • Rehabilitation Science
  • Exercise Physiology

Background:

  • Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by airflow limitation.
  • Assessing functional capacity is crucial for managing severe COPD and understanding its impact on daily life.

Purpose of the Study:

  • To investigate and compare the functional capacity of patients with severe COPD against healthy subjects.
  • To identify key indicators of functional impairment in severe COPD.

Main Methods:

  • The study involved 45 male patients with severe COPD and 45 healthy controls.
  • Evaluations included pulmonary function tests, the 6-minute walk test (6MWT), Borg score, heart rate, and modified Medical Research Council (MRC) dyspnea scale.
  • External work of walking was calculated based on body weight and distance covered.

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Main Results:

  • Severe COPD patients demonstrated significantly lower 6MWT distance and external work compared to healthy controls.
  • No significant differences in 6MWT distance, external work, or exertional dyspnea were observed between moderately severe and very severe COPD groups.
  • In patients with very severe COPD (FEV1 <35%), 6MWT distance correlated with FEV1, MRC, and Borg scores, while external work correlated with age, FEV1, and MRC scores.

Conclusions:

  • Severe COPD patients possess significantly impaired functional capacity relative to healthy individuals.
  • Reduced functional capacity in severe COPD is linked to lung function parameters like FEV1 and subjective measures of breathlessness.
  • The 6MWT is a valuable tool for assessing functional capacity and its determinants in severe COPD patients.