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Updated: Aug 19, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
Published on: April 11, 2019
B cells and autoimmunity 2004: new concepts and therapeutic perspectives
Walid Mourad1, Peter E Lipsky, Moncef Zouali
1Centre de Recherche en Rhumatologie et Immunologie, CHUQ, Pavillon CHUL, 2705 Blvd Laurier, Ste-Foy, Québec, G1V 4G, Canada.
Abstract:
Recently, studies of B-cell physiology have continued to provide new and surprising insights into the nature of autoimmunity, highlighting novel potential immunointervention strategies. The meeting on 'B cells and autoimmunity: new concepts and therapeutic perspectives' brought together basic scientists and clinicians with research interests in a range of autoimmune diseases. Recent advances in different facets of B-cell biology were discussed in the prospect of understanding autoimmunity, and significant advances in our understanding of the mechanisms that regulate the autoimmune response at the B cell-level were described. Even though no single message emerged, it is clear that the B lymphocyte is truly destined to become a therapeutic target for the treatment of autoimmune disease.
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