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Occupational molybdenum exposure and a gouty electrician

Anders I Seldén¹, N Peter Berg, Annika Söderbergh

¹Department of Occupational and Environmental Medicine, Orebro University Hospital, SE-701 85 Orebro, Sweden. anders.selden@orebroll.se

Occupational Medicine (Oxford, England)

|March 11, 2005

Abstract

Background:

Molybdenum is an essential trace element and a component of xanthine oxidase, which catalyses the formation of urate. The toxicity of molybdenum in humans is considered to be low, but hyperuricaemia and gout-like symptoms have been observed sporadically.

Methods:

A case of hyperuricaemia and gouty arthritis in a young man with occupational exposure to molybdenum is described. Improvement during an exposure-free period was followed by a relapse after a reconstruction designed to quantify his molybdenum exposure.

Conclusion:

This case seems to represent the first observation of gout associated with occupational molybdenum exposure, but the association might also be entirely circumstantial.

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