Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Volumetric and projective bone mineral density.

T Fujita1

  • 1Calcium Research Institute, Katsuragi Hospital, Kishiwada, Osaka, Japan. pthfujit@peach.ocn.ne.jp

Journal of Musculoskeletal & Neuronal Interactions
|March 11, 2005
PubMed
Summary

Peripheral computed tomography (pQCT) offers accurate volumetric bone density measurement, distinguishing between trabecular and cortical bone. This advanced technique improves assessment of bone density loss and fracture risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic factors in patients surviving for more than 1 or 5 years after removal of metastatic brain tumors.

Neurologia medico-chirurgica·1992
Same author

Microcirculation of the rat pancreas, with special reference to the insulo-acinar portal and insulo-venous drainage systems: a further scanning electron microscope study of corrosion casts.

Archives of histology and cytology·1992
Same author

Signal transduction through decay-accelerating factor. Interaction of glycosyl-phosphatidylinositol anchor and protein tyrosine kinases p56lck and p59fyn 1.

Journal of immunology (Baltimore, Md. : 1950)·1992
Same author

Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease.

The Journal of experimental medicine·1992
Same author

Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and polysaccharide derivatives.

The Journal of pharmacology and experimental therapeutics·1992
Same author

Role of gastric glutathione in smoke flavouring-induced gastric injury in rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·1992

Area of Science:

  • Orthopedics
  • Radiology
  • Bone Densitometry

Background:

  • Traditional projectional bone mineral density (BMD) methods like absorptiometry have limitations in accurately assessing true bone density.
  • These methods can provide artifactually higher values with increased body size and bone depth due to the omission of a dimension.

Purpose of the Study:

  • To highlight the advantages of peripheral computed tomography (pQCT) over traditional BMD measurements.
  • To emphasize pQCT's capability in accurately measuring volumetric bone density and differentiating between trabecular and cortical bone.
  • To explore the potential of pQCT in assessing bone density loss and bone strength.

Main Methods:

  • Utilizes computed tomography (CT) to measure true volumetric bone density.
  • Applies peripheral computed tomography (pQCT) to the distal and mid-radius, areas rich in cortical bone.
  • Enables separate measurement of trabecular and cortical bone compartments.

Main Results:

  • pQCT provides accurate volumetric bone density, overcoming limitations of projectional methods.
  • Allows for distinct assessment of trabecular and cortical bone, offering new insights into bone density changes.
  • Facilitates dynamic analysis for evaluating bone strength and fracture resistance.

Conclusions:

  • pQCT is a superior method for bone density assessment, providing volumetric and compartment-specific data.
  • This technique offers valuable information for understanding bone density loss from various conditions (e.g., estrogen withdrawal, diabetes).
  • pQCT analysis holds promise for predicting bone strength and reducing fracture risk.

Related Experiment Videos