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Status epilepticus in Indian children in a tertiary care center

Sheffali Gulati1, Veena Kalra, M R Sridhar

  • 1Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

Indian Journal of Pediatrics
|March 11, 2005
PubMed

Insights

Status epilepticus (SE) in children admitted to the PICU requires prompt seizure termination. Early intervention significantly improves outcomes, while prolonged seizures and septic shock increase mortality risk.

Area of Science:

  • Pediatric Intensive Care
  • Neurology
  • Emergency Medicine

Background:

  • Status epilepticus (SE) is a critical neurological emergency in children.
  • Understanding risk factors and outcomes in pediatric SE is crucial for timely management.

Purpose of the Study:

  • To investigate the clinical characteristics, immediate outcomes, and risk factors associated with SE in pediatric patients.
  • To identify factors influencing mortality in children with SE admitted to a tertiary care PICU.

Main Methods:

  • Retrospective analysis of 451 neuroemergency patients admitted to a PICU.
  • Detailed evaluation of 30 pediatric patients diagnosed with status epilepticus.
  • Assessment of clinical presentation, laboratory data, treatment, and outcomes.

Main Results:

  • The study included children aged 1-120 months, with a mean age of 56.6 months.
  • Over half (53.3%) of SE patients had no prior seizure history.
  • Mortality was 30%, significantly associated with seizure duration >45 minutes and septic shock.

Conclusions:

  • Prompt termination of seizure activity is essential for improving immediate outcomes in pediatric SE.
  • Identifying and managing risk factors like prolonged seizures and septic shock can reduce mortality.
Abstract

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