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Related Experiment Videos

Thyroid disorders in pregnancy.

Terence T Lao1

  • 1Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, People's Republic of China. laotth@hkucc.hku.hk

Current Opinion in Obstetrics & Gynecology
|March 11, 2005
PubMed
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Thyroid dysfunction and autoimmunity in pregnant women can negatively impact both maternal and infant health. Early screening and treatment of thyroid disorders are crucial for improving pregnancy outcomes and offspring neurological development.

Area of Science:

  • Reproductive Endocrinology
  • Maternal-Fetal Medicine
  • Thyroidology

Background:

  • Thyroid disorders are common endocrine conditions in pregnant women.
  • Both overt and subclinical thyroid dysfunction, including hypothyroidism and autoimmunity, are linked to adverse reproductive outcomes.
  • These conditions can have short- and long-term consequences for both mother and child.

Purpose of the Study:

  • To provide an updated review of thyroid disorders in pregnancy, revising traditional views.
  • To highlight the association between thyroid dysfunction and adverse reproductive outcomes.
  • To emphasize the importance of screening and treatment for thyroid disorders during pregnancy.

Main Methods:

  • This is a review article, synthesizing existing literature on thyroid disorders in pregnancy.

Related Experiment Videos

  • It examines the impact of hypothyroidism, subclinical hypothyroidism, and thyroid autoimmunity.
  • The review discusses screening, treatment, and the role of iodine and antibodies.

    • Main Results:

    • Thyroid disorders are the most frequent pre-gestational endocrine issues in pregnant individuals.
    • Hypothyroidism, particularly subclinical forms, significantly affects pregnancy and offspring neurological development.
    • Thyroid antibodies and iodine deficiency also play a role in pregnancy outcomes.

    Conclusions:

    • Even in clinically euthyroid women, biochemical abnormalities or thyroid autoimmunity can impact obstetric and infant neurological outcomes.
    • Screening for thyroid function and autoimmunity, followed by timely treatment, is essential for better pregnancy results.
    • Infants born to mothers with thyroid disorders require assessment, and potentially ongoing monitoring and treatment of their thyroid function.