Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Does fibrin sealant decrease immediate urinary leakage following radical retropubic prostatectomy?

Eric K Diner1, Sunil V Patel, Arnold M Kwart

  • 1Department of Urology, Washington Hospital Center, Washington, DC 20010, USA. ericdiner@hotmail.com

The Journal of Urology
|March 11, 2005
PubMed
Summary

Fibrin sealant significantly reduced urinary leakage after radical retropubic prostatectomy, leading to earlier drain removal. This application improves patient comfort and may expedite hospital discharge.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Temporal trends in colorectal resections for benign colorectal neoplasia: A retrospective cohort study of the ACS-NSQIP 2016-2022.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2026
Same author

Preoperative low-energy diets for patients with a body mass index >30 kg/m2 undergoing non-bariatric surgery: pilot feasibility randomized clinical trial and a systematic review and meta-analysis of efficacy data.

The British journal of surgery·2026
Same author

Intracorporeal Side-to-End Anastomosis During Robotic Stapled Circular Anastomosis: A Primer.

Diseases of the colon and rectum·2025
Same author

Fragmentation of Multimodal Rectal Cancer Care: A Population-Level Retrospective Cohort Study.

Journal of surgical oncology·2025
Same author

Local excision for T1 rectal cancer: A population-based study of practice patterns and oncological outcomes.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2025
Same author

An assessment of cancer centre level designation and guideline adherent care in those with rectal cancer: A population based retrospective cohort study.

Journal of cancer policy·2024

Area of Science:

  • Urology
  • Surgical Innovation
  • Medical Devices

Background:

  • Radical retropubic prostatectomy is a common procedure for prostate cancer.
  • Postoperative urinary leakage can complicate recovery.
  • Minimizing drain output is crucial for patient comfort and early discharge.

Purpose of the Study:

  • To evaluate the effectiveness of fibrin sealant in reducing urinary leakage after radical retropubic prostatectomy.
  • To assess the impact of fibrin sealant on postoperative drain output and drain removal timing.

Main Methods:

  • A comparative study of 32 patients undergoing radical retropubic prostatectomy.
  • 16 patients received standard technique (control group).
  • 16 patients received fibrin sealant applied to the urethrovesical anastomosis.

Related Experiment Videos

Main Results:

  • The fibrin sealant group showed significantly less overall drain output (p = 0.005).
  • Earlier drain removal was achieved in 100% of the fibrin sealant group versus 81% of the control group.
  • No immediate adverse events were associated with fibrin sealant use.

Conclusions:

  • Fibrin sealant effectively decreases postoperative drain output following radical retropubic prostatectomy.
  • Early drain removal, facilitated by fibrin sealant, can enhance patient comfort and potentially shorten hospital stays.
  • Fibrin sealant is a safe adjunct for reducing urinary leakage in prostatectomy patients.