Related Experiment Video
Updated: Aug 19, 2026

13:55
Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
Published on: February 3, 2013
Misuse of the Pearson chi-square test of association
Archives of Physical Medicine and Rehabilitation
|March 11, 2005
Abstract
No abstract available in PubMed .
Related Concept Videos
Chi-square Analysis
The chi-square test is a statistical hypothesis test. It is used to check whether there is a significant difference between an expected value and an observed value. In the context of genetics, it enables us to either accept or reject a hypothesis, based on how much the observed values deviate from the expected values.
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...
Test for Homogeneity
The goodness–of–fit test can be used to decide whether a population fits a given distribution, but it will not suffice to decide whether two populations follow the same unknown distribution. A different test, called the test for homogeneity, can be used to conclude whether two populations have the same distribution. To calculate the test statistic for a test for homogeneity, follow the same procedure as with the test of independence. The hypotheses for the test for homogeneity can be stated as...
Chi-square Distribution
How does one determine if bingo numbers are evenly distributed or if some numbers occurred with a greater frequency? Or if the types of movies people preferred were different across different age groups or if a coffee machine dispensed approximately the same amount of coffee each time. These questions can be addressed by conducting a hypothesis test. One distribution that can be used to find answers to such questions is known as the chi-square distribution. The chi-square distribution has...
Introduction to Test of Independence
In statistics, the term independence means that one can directly obtain the probability of any event involving both variables by multiplying their individual probabilities. Tests of independence are chi-square tests involving the use of a contingency table of observed (data) values.
The test statistic for a test of independence is similar to that of a goodness-of-fit test:
The test statistic for a test of independence is similar to that of a goodness-of-fit test:
Hypothesis Test for Test of Independence
The test of independence is a chi-square-based test used to determine whether two variables or factors are independent or dependent. This hypothesis test is used to examine the independence of the variables. One can construct two qualitative survey questions or experiments based on the variables in a contingency table. The goal is to see if the two variables are unrelated (independent) or related (dependent). The null and alternative hypotheses for this test are:
H0: The two variables (factors)...
H0: The two variables (factors)...
Fisher's Exact Test
Fisher's exact test is a statistical significance test widely used to analyze 2x2 contingency tables, particularly in situations where sample sizes are small. Unlike the chi-squared test, which approximates P-values and assumes minimum expected frequencies of at least five in each cell, Fisher's exact test calculates the exact probability (P-value) of observing the data or more extreme results under the null hypothesis. This feature makes it especially valuable when the assumptions of the...
