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Updated: Aug 19, 2026

Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking (TXL) for Myopia
Published on: January 6, 2018
[An experimental action of new injection-scleroplasty substance on eye tissues]
Abstract:
An experimental study was made with 8 eyes of chinchilla rabbits for the purpose of investigating the interplay between the allotransplant (administered in the Tenon's space of the eyes of experimental animals), suggested by us, on the one hand, and the neighboring ocular components, on the other hand. According to the results, the used substance is subject to necrolysis accompanied by an induced local inflammation response. As the substance dissolved, it was found to be displaced by connective tissue. At first, the tissue was granulated, then, it became more compact with its structure resembling the sclera; the tissue tightly abutted the latter intensifying its properties. It is noteworthy, that the inflammation zone was limited to the administration region. With due respect to the above, it can be stated that the suggested method can be clinically used in future as a full sclera-fixing procedure.

