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Published on: May 27, 2015
Campylobacter infections of the pericardium and myocardium
1Norfolk and Norwich University Hospital, Norwich, Norfolk, UK. chika@doctors.org.uk
Abstract:
Members of the genus Campylobacter are notorious for their ability to cause gastroenteritis. However, increasing numbers of case reports now suggest that they may have a wider pathogenic repertoire. Pericarditis and myocarditis are increasingly being recognised as sequelae of Campylobacter infection. Although rare, these presentations are important, as misdiagnosis may result in inappropriate thrombolysis or angioplasty, with potential accompanying complications. Extraintestinal Campylobacter infections, and the resulting pathogenesis, remain an important challenge for the 21st century, particularly as immunocompromised patients are likely to become increasingly common.
Insights
Campylobacter infections can cause more than gastroenteritis, including rare heart conditions like pericarditis and myocarditis. Early diagnosis is crucial to prevent complications, especially in immunocompromised individuals.
Area of Science:
- Microbiology
- Infectious Diseases
- Cardiology
Background:
- Campylobacter species are primarily known for causing gastroenteritis.
- Emerging evidence indicates a broader pathogenic potential for Campylobacter.
- Case reports highlight Campylobacter as a cause of pericarditis and myocarditis.
Discussion:
- Pericarditis and myocarditis are rare but significant sequelae of Campylobacter infection.
- Misdiagnosis of these cardiac conditions can lead to inappropriate treatments like thrombolysis or angioplasty.
- Extraintestinal manifestations of Campylobacter pose a growing challenge.
Key Insights:
- Campylobacter's role extends beyond gastrointestinal infections.
- Cardiac involvement (pericarditis, myocarditis) is an under-recognized complication.
- Accurate diagnosis is vital to guide appropriate patient management and avoid iatrogenic harm.
Outlook:
- The increasing prevalence of immunocompromised patients may lead to more frequent extraintestinal Campylobacter infections.
- Further research is needed to understand the pathogenesis of these rare complications.
- Enhanced surveillance and diagnostic strategies are required to address this evolving public health concern.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Pericarditis I: Introduction
Pericarditis II: Clinical Features and Diagnostic Tests

