Intracellular free magnesium in lymphocytes from patients with congestive cardiac failure treated with loop diuretics

¹Department of Pharmacology & Therapeutics, Leicester Royal Infirmary.

British Journal of Clinical Pharmacology

|March 1, 1992

Abstract:

Cellular Mg2+ depletion has been reported in patients on long term diuretic therapy. We therefore measured lymphocyte free Mg2+ concentrations in patients with congestive cardiac failure treated with loop diuretics or a frusemide/amiloride mixture (Frumil) and compared them with control subjects. There was no correlation between lymphocyte free Mg2+ levels and plasma Mg2+ concentrations. Patients treated with loop diuretics did not show lymphocyte intracellular free Mg2+ depletion compared with normal controls, and those on Frumil showed higher intracellular free Mg2+ levels than normal.

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Intracellular free magnesium in lymphocytes from patients with congestive cardiac failure treated with loop diuretics...

Abstract:

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Intracellular free magnesium in lymphocytes from patients with congestive cardiac failure treated with loop diuretics