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Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
Published on: July 3, 2015
Frequency of chromosomal lesions and damaged lymphocytes of workers occupationally exposed to x rays
1Faculty of Medicine, University of Belgrade Institute of Occupational Medicine and Radiological Protection, Deligradska 29 11000 Belgrade, Serbia and Montenegro. smilacic@afrodita.rcub.bg.ac.yu
Abstract:
This paper analyzes the effects of x rays on workers exposed to radiation. In particular, this paper documents the emergence and frequency of non-specific chromosomal lesions with characteristic chromosomal aberrations and the number of damaged lymphocytes before, during, and after occupational exposure. Chromosomal changes were analyzed taking into consideration duration of exposure, dose, age, and sex. Correlation between aberrations and absorbed doses of x rays measured by thermoluminescence dosimeters is shown, as well as correlation between chromosomal lesions and damaged cells and the frequency of chromosomal aberrations. Chromosomal aberrations of karyotype diminish after exposures cease, but the number of non-specific lesions in karyotype do not decrease during the same period. The duration of exposure and age are not significant predictors of analyzed aberrations and lesions.
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