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Pediatric heart transplantation for doxorubicin-induced cardiomyopathy
1Department of Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee 53226.
Abstract:
The prognosis of patients with a history of successfully treated malignancy, who subsequently undergo organ transplantation and long-term immunosuppression, is uncertain. We report the case of a 14-year-old girl in whom doxorubicin-induced cardiomyopathy developed after aggressive therapy for a fibroblastic osteosarcoma. The patient underwent orthotopic heart transplantation and remains in remission 14 months after surgery.