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Updated: Aug 19, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Within-subject testing of the signaled-reinforcement effect on operant responding as measured by response rate and
1Department of Psychology, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, United Kingdom. p.reed@swansea.ac.uk
Abstract:
Response rates under random-interval schedules are lower when a brief (500 ms) signal accompanies reinforcement than when there is no signal. The present study examined this signaled-reinforcement effect and its relation to resistance to change. In Experiment 1, rats responded on a multiple random-interval 60-s random-interval 60-s schedule, with signaled reinforcement in only one component. Response resistance to alternative reinforcement, prefeeding, and extinction was compared between these components. Lower response rates, and greater resistance to change, occurred in the component with the reinforcement signal. In Experiment 2, response rates and resistance to change were compared after training on a multiple random-interval 60-s random-interval 60-s schedule in which reinforcer delivery was unsignaled in one component and a response-produced uncorrelated stimulus was presented in the other component. Higher response rates and greater resistance to change occurred with the uncorrelated stimulus. These results highlight the significance of considering the effects of an uncorrelated signal when used as a control condition, and challenge accounts of resistance to change that depend solely on reinforcer rate.
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