Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Sucrose saturated solution bioactivity over Sporothrix schenckii].

M G Medvedeff1, M Celina-Vedoya, M A Lloret

  • 1Beato Roque Gonzalez 835, Posadas (3300) Misiones República Argentina. mmedve@infovia.com.ar

Revista Iberoamericana De Micologia
|March 15, 2005
PubMed
Summary

A novel sucrose saturated solution with eugenol and polyethylenglycol 400 effectively inhibited Sporothrix schenkii growth in vitro. Fungal viability ceased after two minutes of exposure, suggesting potential for sporotrichosis treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Minor cutaneous ambulatory surgery and cryotherapy. Comparative study between a dermatologist and family physicians].

Actas dermo-sifiliograficas·2007
Same author

Prevalence of pulmonary tuberculosis and comparative evaluation of screening strategies in a Brazilian prison.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2005
Same author

[Fibrinogen and factor VII in women with dyslipidemia. The preliminary results of the Bellvitge-Costa de Ponent Study. The Bellvitge Study Group].

Medicina clinica·1995
Same author

Effect of potassium sorbate and pH on the survival of Staphylococcus aureus in saturated sugar solutions.

Revista Argentina de microbiologia·1993
Same author

Do knowledge and attitudes about influenza and its immunization affect the likelihood of obtaining immunization?

Family practice research journal·1992
Same author

[Compliance of antibiotic treatment in primary health care. Value of the personalized prescription].

Revista clinica espanola·1989

Area of Science:

  • Mycology
  • Antimicrobial agents
  • Fungal physiology

Context:

  • Sporothrix schenkii is a dimorphic fungus responsible for sporotrichosis, a significant cutaneous infection.
  • Current treatments for sporotrichosis can be limited, necessitating exploration of alternative therapeutic agents.
  • Understanding the susceptibility of S. schenkii to various chemical compounds is crucial for developing new interventions.

Purpose:

  • To evaluate the in vitro bioactivity of a specific sucrose saturated solution containing eugenol and polyethylenglycol 400.
  • To determine the efficacy of this solution against the fungal pathogen Sporothrix schenkii.

Summary:

  • A suspension of Sporothrix schenkii was exposed to the test solution, and viability was assessed over time.
  • Complete fungal death was observed after 2 minutes of contact with the sucrose saturated solution.

Related Experiment Videos

  • The fungicidal effect is hypothesized to result from cellular dehydration due to the solution's low water activity.

    • Impact:

    • This study demonstrates the potent in vitro antifungal activity of the eugenol and polyethylenglycol 400 saturated solution against Sporothrix schenkii.
    • The findings suggest this solution holds potential as a novel agent for managing sporotrichosis.
    • Further research into the mechanism of action and in vivo efficacy is warranted.