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Published on: January 25, 2015
Uveal melanoma: proton beam irradiation
Evangelos S Gragoudas1, Anne Marie Lane
1Department of Ophthalmology, Harvard Medical School, and Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA. evangelos_gragoudas@meei.harvard.edu
Ophthalmology Clinics of North America
|March 15, 2005
Summary
Proton therapy is now the standard treatment for uveal melanoma, replacing enucleation. While it doesn't improve survival, proton therapy preserves the eye and sometimes vision.
Area of Science:
- Ophthalmology
- Radiation Oncology
- Oncology
Background:
- Radiotherapy has become the standard treatment for uveal melanoma over the last 20 years.
- This shift has occurred because radiotherapy preserves the globe and, in some cases, visual function, unlike enucleation.
Purpose of the Study:
- To present the authors' and other investigators' experiences with proton therapy for uveal melanoma.
Main Methods:
- Review of clinical experience with proton therapy for uveal melanoma.
- Analysis of outcomes including globe preservation and visual function.
Main Results:
- Proton therapy has replaced enucleation as the standard treatment for uveal melanoma.
- While survival rates are not altered, globe and visual function preservation are achieved.
Conclusions:
- Proton therapy is an effective treatment for uveal melanoma, offering globe and visual function preservation.
- The authors' and other investigators' experiences support the use of proton therapy in managing uveal melanoma.
