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Updated: Feb 17, 2026

Preparation and Evaluation of 99mTc-labeled Tridentate Chelates for Pre-targeting Using Bioorthogonal Chemistry
Published on: February 4, 2017
New oxorhenium(V) complexes with 2N2S donor sets and radiochemical behavior of their technetium analogs
Pulak K Dhara1, Biswajit Das, Jem-Mau Lo
1Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713104, India.
Abstract:
Oxorhenium(V) complexes of two thioether amines have been synthesized and characterized spectroscopically. The five-coordinated ReO(3+) moiety is satisfied by the amine compounds behaving as dibasic tetradentate (NSSN) ligands and a chloride ion. The radioanalytical studies of their technetium analogs have been carried out at different pH values in the range 3-10. The solvent extraction, TLC, electrophoresis and HPLC studies using (99m)Tc radiotracer indicate that the labeled complex with the TcO(3+) core is similar to the rhenium complex with the ReO(3+) core.
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