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Hypergravity exercise against bed rest induced changes in cardiac autonomic control.

Ken-Ichi Iwasaki1, Tomoki Shiozawa, Atsunori Kamiya

  • 1Department of Hygiene and Space Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-Kamimachi, Itabasi-ku, Tokyo 173-8610, Japan. kiwasaki@med.nihon-u.ac.jp

European Journal of Applied Physiology
|March 15, 2005
PubMed
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Artificial hypergravity with exercise may counteract heart rate regulation issues after spaceflight. This countermeasure preserved parasympathetic activity and baroreflex function during head-down-tilt bed rest.

Area of Science:

  • Space Physiology
  • Cardiovascular Regulation
  • Autonomic Nervous System

Background:

  • Spaceflight leads to physiological deconditioning, including impaired autonomic cardiovascular control.
  • Artificial hypergravity with exercise is being investigated as a potential countermeasure to mitigate these effects.

Purpose of the Study:

  • To investigate the efficacy of intermittent artificial hypergravity exposure with ergometric exercise as a countermeasure against alterations in autonomic cardiovascular control during simulated weightlessness.

Main Methods:

  • Twelve male subjects underwent 14 days of head-down-tilt bed rest (HDBR).
  • The countermeasure (CM) group (n=6) received intermittent hypergravity (+1.2 Gz) with ergometric exercise during HDBR.
  • The control group (n=6) did not receive the countermeasure.

Related Experiment Videos

  • Autonomic cardiovascular control was assessed by measuring blood pressure and ECG before and after HDBR.

    • Main Results:

    • The control group showed significant decreases in cardiac parasympathetic activity (high frequency power of R-R interval) and vagally mediated arterial-cardiac baroreflex function (transfer function gain HF) after HDBR.
    • These significant decreases were not observed in the countermeasure group.
    • Baroreflex gain analysis by sequence method corroborated these findings.

    Conclusions:

    • Intermittent exposure to artificial hypergravity with ergometric exercise may attenuate the negative effects of weightlessness on parasympathetic activity.
    • This countermeasure approach shows promise in preserving spontaneous arterial-cardiac baroreflex function after simulated spaceflight.